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The company’s progress in developing a treatment for aggressive non-Hodgkin’s lymphoma is encouraging, with more than one-third of participants in one study showing no sign of disease six months after treatment.This promising study and Kite Pharma’s other endeavours have seen the company snapped up by Gilead Sciences, a biopharma giant with a .36bn market value.If you don’t recognise this Shenzhen company by name, you will have likely heard of its primary product, We Chat, the massive social network that even the likes of Facebook aspires to emulate.Much more than just a media-sharing platform for its 770m-plus dedicated daily users, We Chat supports messaging, videos and music alongside online gaming, shopping and peer-to-peer payments, all through one convenient, and ubiquitous, mobile app.

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Another biotech company, Regeneron mines data on the human genome to find targets for specific diseases in order to produce monoclonal antibodies that hit those targets.“Though they might be unfamiliar to you today, we believe they have an inside track to take advantage of the technologies, such as artificial intelligence, that will define business in the coming years,” wrote editor David Rotman.“Being smart about innovation won’t guarantee that these firms become superstars.Three newcomers – i Flytek, Kite Pharma and Regeneron – shot straight into the top 10, while US pharma company Merck makes its debut at No 17.So, which are the top 10 smartest companies in the world? Philadelphia biotech Spark Therapeutics is still at the clinical stage with its products, but its pipeline is promising revolutionary gene therapy for some devastating diseases such as a progressive form of blindness known as choroideremia.Gilead recently acquired Kite Pharma for .9bn, with the deal expected to close in the fourth quarter of this year.

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